This is a complete list of the songs that reached number one on the Pop 100 chart from its inception in February 2005 through it discontinuation in June 2009. Its airplay points were compiled from electronic monitoring of approximately 115 mainstream Top 40 stations by Nielsen Broadcast Data Systems.


The chart debuted in the issue dated February 12, 2005, with the first number one being "1, 2 Step" by Ciara featuring Missy Elliott. The number-one song on the final chart in the issue dated June 27, 2009, was "Boom Boom Pow" by The Black Eyed Peas.