Cerebral hemisphere
The vertebrate cerebrum (brain) is formed by two cerebral hemispheres that are separated by a groove, the longitudinal fissure. The brain can thus be described as being divided into left and right cerebral hemispheres. Each of these hemispheres has an outer layer of grey matter, the cerebral cortex, that is supported by an inner layer of white matter. In eutherian (placental) mammals, the hemispheres are linked by the corpus callosum, a very large bundle of nerve fibers. Smaller commissures, including the anterior commissure, the posterior commissure and the fornix, also join the hemispheres and these are also present in other vertebrates. These commissures transfer information between the two hemispheres to coordinate localized functions.
Not to be confused with Cerebellar hemisphere.Cerebral hemisphere
There are three known poles of the cerebral hemispheres: the occipital pole, the frontal pole, and the temporal pole.
The central sulcus is a prominent fissure which separates the parietal lobe from the frontal lobe and the primary motor cortex from the primary somatosensory cortex.
Macroscopically the hemispheres are roughly mirror images of each other, with only subtle differences, such as the Yakovlevian torque seen in the human brain, which is a slight warping of the right side, bringing it just forward of the left side. On a microscopic level, the cytoarchitecture of the cerebral cortex, shows the functions of cells, quantities of neurotransmitter levels and receptor subtypes to be markedly asymmetrical between the hemispheres.[1][2] However, while some of these hemispheric distribution differences are consistent across human beings, or even across some species, many observable distribution differences vary from individual to individual within a given species.
Clinical significance[edit]
Infarcts of the centrum ovale can occur.[3]
As a treatment for epilepsy the corpus callosum may be severed to cut the major connection between the hemispheres in a procedure known as a corpus callosotomy.
A hemispherectomy is the removal or disabling of one of the hemispheres of the brain. This is a rare procedure used in some extreme cases of seizures which are unresponsive to other treatments.
The sheep brain seen from the back. Opening longitudinal fissure which separates left and right cerebral hemispheres.
Lateral surface. (The frontal pole is approximately at 10, the occipital pole is approximately at 17, and the temporal pole is approximately at 38.)
