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Citric acid

Citric acid is an organic compound with the chemical formula HOC(CO2H)(CH2CO2H)2.[10] It is a colorless weak organic acid.[10] It occurs naturally in citrus fruits. In biochemistry, it is an intermediate in the citric acid cycle, which occurs in the metabolism of all aerobic organisms.[10]

"E330" redirects here. For the locomotive, see FS Class E330.

More than two million tons of citric acid are manufactured every year. It is used widely as an acidifier, as a flavoring, and a chelating agent.[11]


A citrate is a derivative of citric acid; that is, the salts, esters, and the polyatomic anion found in solutions and salts of citric acid. An example of the former, a salt is trisodium citrate; an ester is triethyl citrate. When citrate trianion is part of a salt, the formula of the citrate trianion is written as C
6
H
5
O3−
7
or C
3
H
5
O(COO)3−
3
.

Safety[edit]

Although a weak acid, exposure to pure citric acid can cause adverse effects. Inhalation may cause cough, shortness of breath, or sore throat. Over-ingestion may cause abdominal pain and sore throat. Exposure of concentrated solutions to skin and eyes can cause redness and pain.[51] Long-term or repeated consumption may cause erosion of tooth enamel.[51][52][53]

[54]

British Pharmacopoeia

[55]

Japanese Pharmacopoeia

The closely related acids , aconitic acid, and propane-1,2,3-tricarboxylic acid (tricarballylic acid, carballylic acid)

isocitric acid

Acids in wine