Craig Mello
Craig Cameron Mello (born October 18, 1960) is an American biologist and professor of molecular medicine at the University of Massachusetts Medical School in Worcester, Massachusetts. He was awarded the 2006 Nobel Prize for Physiology or Medicine, along with Andrew Z. Fire, for the discovery of RNA interference. This research was conducted at the University of Massachusetts Medical School and published in 1998. Mello has been a Howard Hughes Medical Institute investigator since 2000.[1]
Craig Cameron Mello
October 18, 1960
Wiley Prize (2003)
NAS Award in Molecular Biology (2003)
Massry Prize (2005)
Gairdner Foundation International Award (2005)
Nobel Prize in Physiology or Medicine (2006)
Early life[edit]
Mello was born in New Haven, Connecticut on October 18, 1960.[2] He was the third child of James and Sally Mello. His father, James Mello, was a paleontologist and his mother, Sally Mello, was an artist.[2] His paternal grandparents immigrated to the US from the Portuguese islands of Azores. His parents met while attending Brown University and were the first children in their respective families to attend college. His grandparents on both sides withdrew from school as teenagers to work for their families.[2] James Mello completed his Ph.D. in paleontology from Yale University in 1962. The Mello family moved to Falls Church in northern Virginia so that James could take a position with the United States Geological Survey (USGS) in Washington, DC.[2] He was raised as Roman Catholic.[2]
After a brief stay in Falls Church, the family moved to Fairfax, Virginia, when James Mello switched from the USGS to a position as assistant director at the Smithsonian Museum of Natural History.[2] Among Craig's fondest early memories were field trips with his father and the whole family to Colorado and Wyoming and more frequent trips to the Blue Ridge mountains in Virginia.[2]
The Mello family had a very strong tradition of discussions around the dinner table and this experience was very important to young Mello. He learned to argue, to listen, and to admit it when he was wrong about something. At a time when young Mello was not performing so well in school, these daily discussions helped to build his confidence and self-esteem.[2] Mello struggled during the first few years of grade school. He started first grade at the age of five in a local private school because he was too young to enter first grade in the public system. He doesn't know if he was a slow learner, or just not interested, but he did not do well in school until the seventh grade. In second grade, Mello only pretended that he could read and he was embarrassed by being called on in class.[2] He much preferred playing outdoors, in the woods and creeks, to time spent in the classroom.[2] Meanwhile, his older siblings were model students, raising the teacher's expectations for him. During these early years, Mello had no doubt that he would be a scientist when he grew up. He is now the father of two daughters and a step-daughter and step-son.[2]
Involvement in RNAi biotechnology industry[edit]
Mello is involved in several RNAi-based biotechnology companies. He is a co-founder of RXi Pharmaceuticals where he Chairs the Scientific Advisory Board. In June 2010, he joined the Technology Advisory Board of Beeologics, a company focused on development of RNAi products for honeybee health and various veterinary and agricultural applications, which, according to Mello, "could very well be the first company to obtain FDA approval for an RNAi therapy".[8] In September 2011 Monsanto acquired Beeologics.
(By chronological year of award [9])