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Implant (medicine)

An implant is a medical device manufactured to replace a missing biological structure, support a damaged biological structure, or enhance an existing biological structure. For example, an implant may be a rod, used to strengthen weak bones. Medical implants are human-made devices, in contrast to a transplant, which is a transplanted biomedical tissue. The surface of implants that contact the body might be made of a biomedical material such as titanium, silicone, or apatite depending on what is the most functional.[1] In 2018, for example, American Elements developed a nickel alloy powder for 3D printing robust, long-lasting, and biocompatible medical implants.[2] In some cases implants contain electronics, e.g. artificial pacemaker and cochlear implants. Some implants are bioactive, such as subcutaneous drug delivery devices in the form of implantable pills or drug-eluting stents.[3]

Classification[edit]

United States classification[edit]

Medical devices are classified by the US Food and Drug Administration (FDA) under three different classes depending on the risks the medical device may impose on the user. According to 21CFR 860.3, Class I devices are considered to pose the least amount of risk to the user and require the least amount of control. Class I devices include simple devices such as arm slings and hand-held surgical instruments. Class II devices are considered to need more regulation than Class I devices and are required to undergo specific requirements before FDA approval. Class II devices include X-ray systems and physiological monitors. Class III devices require the most regulatory controls since the device supports or sustains human life or may not be well tested. Class III devices include replacement heart valves and implanted cerebellar stimulators. Many implants typically fall under Class II and Class III devices.[20][21]

ASTM F138/F139

316L

ASTM F1314 22Cr-13Ni–5Mn

Drug-eluting implant

Biofunctionalisation

Implantable devices

List of orthopedic implants

Medical device

Prosthesis

Microchip implant

(in French) scandal by ICIJ, November 2018.

Implant Files

AAOMS - Dental Implant Surgery

ACOG - IUDs and Birth Control Implants: Resource Overview

FDA - Implants and Prosthetics

– Recalls, Safety Alerts and Field Safety Notices of medical devices – International Consortium of Investigative Journalists

International Medical Devices Database

Implant-Register