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Protein (nutrient)

Proteins are essential nutrients for the human body.[1] They are one of the building blocks of body tissue and can also serve as a fuel source. As a fuel, proteins provide as much energy density as carbohydrates: 4 kcal (17 kJ) per gram; in contrast, lipids provide 9 kcal (37 kJ) per gram. The most important aspect and defining characteristic of protein from a nutritional standpoint is its amino acid composition.[2]

This article is about protein as a nutrient. For protein as a class of molecule, see Protein. For other uses, see Bodybuilding supplement.

Proteins are polymer chains made of amino acids linked together by peptide bonds. During human digestion, proteins are broken down in the stomach to smaller polypeptide chains via hydrochloric acid and protease actions. This is crucial for the absorption of the essential amino acids that cannot be biosynthesized by the body.[3]


There are nine essential amino acids which humans must obtain from their diet in order to prevent protein-energy malnutrition and resulting death. They are phenylalanine, valine, threonine, tryptophan, methionine, leucine, isoleucine, lysine, and histidine.[2][4] There has been debate as to whether there are 8 or 9 essential amino acids.[5] The consensus seems to lean towards 9 since histidine is not synthesized in adults.[6] There are five amino acids which humans are able to synthesize in the body. These five are alanine, aspartic acid, asparagine, glutamic acid and serine. There are six conditionally essential amino acids whose synthesis can be limited under special pathophysiological conditions, such as prematurity in the infant or individuals in severe catabolic distress. These six are arginine, cysteine, glycine, glutamine, proline and tyrosine.[2] Dietary sources of protein include grains, legumes,[7] nuts,[8] seeds,[7] meats, dairy products, fish, eggs, edible insects, and seaweeds.[9]

Protein functions in human body[edit]

Protein is a nutrient needed by the human body for growth and maintenance. Aside from water, proteins are the most abundant kind of molecules in the body. Protein can be found in all cells of the body and is the major structural component of all cells in the body, especially muscle. This also includes body organs, hair and skin. Proteins are also used in membranes, such as glycoproteins. When broken down into amino acids, they are used as precursors to nucleic acid, co-enzymes, hormones, immune response, cellular repair, and other molecules essential for life. Additionally, protein is needed to form blood cells.[1][2]

Azotorrhea

Biological value

Bodybuilding supplement

Leaf protein concentrate

Low-protein diet

Ninja diet

Protein bar

Single-cell protein

List of proteins in the human body