Protein targeting
Protein targeting or protein sorting is the biological mechanism by which proteins are transported to their appropriate destinations within or outside the cell.[1][2][note 1] Proteins can be targeted to the inner space of an organelle, different intracellular membranes, the plasma membrane, or to the exterior of the cell via secretion.[1][2] Information contained in the protein itself directs this delivery process.[2][3] Correct sorting is crucial for the cell; errors or dysfunction in sorting have been linked to multiple diseases.[2][4][5]
Protein transport is defective in the following genetic diseases: