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Puberty

Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. It is initiated by hormonal signals from the brain to the gonads: the ovaries in a female, the testicles in a male. In response to the signals, the gonads produce hormones that stimulate libido and the growth, function, and transformation of the brain, bones, muscle, blood, skin, hair, breasts, and sex organs. Physical growth—height and weight—accelerates in the first half of puberty and is completed when an adult body has been developed. Before puberty, the external sex organs, known as primary sexual characteristics, are sex characteristics that distinguish males and females. Puberty leads to sexual dimorphism through the development of the secondary sex characteristics, which further distinguish the sexes.

"Sexual development" redirects here. For sexual development of non-human organisms, see Sexual maturity.

On average, females begin puberty at ages 10–11 and complete puberty at ages 15–17; males generally begin puberty at ages 11–12 and complete puberty at ages 16–17.[1][2][3] The major landmark of puberty for females is menarche, the onset of menstruation, which occurs on average between ages 12 and 13.[2] For males, first ejaculation, spermarche, occurs on average at age 13.[4] In the 21st century, the average age at which children, especially females, reach specific markers of puberty is lower compared to the 19th century, when it was 15 for females and 17 for males (with age at first periods for females and voice-breaks for males being used as examples).[5] This can be due to any number of factors, including improved nutrition resulting in rapid body growth, increased weight and fat deposition,[6] or exposure to endocrine disruptors such as xenoestrogens, which can at times be due to food consumption or other environmental factors.[7][8] However, more modern archeological research suggests that the rate of puberty as it occurs now is the intended way. Growth spurts began at around 10–12, but markers of later stages of puberty such as menarche had delays that correlated with severe environmental conditions such as poverty, poor nutrition, air and pollution.[9][10][11] Puberty that starts earlier than usual is known as precocious puberty, and puberty which starts later than usual is known as delayed puberty.


Notable among the morphologic changes in size, shape, composition, and functioning of the pubertal body, is the development of secondary sex characteristics, the "filling in" of the child's body; from girl to woman, from boy to man. Derived from the Latin puberatum (age of maturity), the word puberty describes the physical changes to sexual maturation, not the psychosocial and cultural maturation denoted by the term adolescent development in Western culture, wherein adolescence is the period of mental transition from childhood to adulthood, which overlaps much of the body's period of puberty.[12]

(a tachykinin peptide) and kisspeptin (a neuropeptide), both present in KNDy neurons of the hypothalamus, are critical parts of the control system that switches on the release of GnRH at the start of puberty.[89]

Neurokinin B

(gonadotropin-releasing hormone) is a peptide hormone released from the hypothalamus which stimulates gonadotrope cells of the anterior pituitary.

GnRH

(luteinizing hormone) is a larger protein hormone secreted into the general circulation by gonadotrope cells of the anterior pituitary gland. The main target cells of LH are the Leydig cells of testes and the theca cells of the ovaries. LH secretion changes more dramatically with the initiation of puberty than FSH, as LH levels increase about 25-fold with the onset of puberty, compared with the 2.5-fold increase of FSH.

LH

(follicle stimulating hormone) is another protein hormone secreted into the general circulation by the gonadotrope cells of the anterior pituitary. The main target cells of FSH are the ovarian follicles and the Sertoli cells and spermatogenic tissue of the testes.

FSH

is a steroid hormone produced primarily by the Leydig cells of the testes, and in lesser amounts by the theca cells of the ovaries and the adrenal cortex. Testosterone is the primary mammalian androgen and the "original" anabolic steroid. It acts on androgen receptors in responsive tissue throughout the body.

Testosterone

is a steroid hormone produced by aromatization of testosterone. Estradiol is the principal human estrogen and acts on estrogen receptors throughout the body. The largest amounts of estradiol are produced by the granulosa cells of the ovaries, but lesser amounts are derived from testicular and adrenal testosterone.

Estradiol

androgens are steroids produced by the zona reticulosa of the adrenal cortex in both sexes. The major adrenal androgens are dehydroepiandrosterone, androstenedione (which are precursors of testosterone), and dehydroepiandrosterone sulfate which is present in large amounts in the blood. Adrenal androgens contribute to the androgenic events of early puberty in females.

Adrenal

(insulin-like growth factor 1) rises substantially during puberty in response to rising levels of growth hormone and may be the principal mediator of the pubertal growth spurt.

IGF1

is a protein hormone produced by adipose tissue. Its primary target organ is the hypothalamus. The leptin level seems to provide the brain a rough indicator of adipose mass for purposes of regulation of appetite and energy metabolism. It also plays a permissive role in female puberty, which usually will not proceed until an adequate body mass has been achieved.

Leptin

(approximately age 6)

adrenarche

(approximately age 8)

gonadarche

(approximately age 11 in females)

thelarche

(approximately age 12)

pubarche

(approximately age 12.5 in females)

menarche

(approximately age 13.5 in males[102])

spermarche

(archive)

Support for teens

University of Maryland guide to puberty and adolescence

Growing Up Sexually: A World Atlas

Pictures and detailed information about breast development during puberty

Puberty in females: interactive animation of Tanner stages

Puberty in males: interactive animation of Tanner stages