Replication timing

Replication timing and disease[edit]

Another intriguing aspect of replication timing is that the temporal order of replication is disrupted in most cancers and in many diseases.^[18] We do not yet understand the mechanisms behind this link, but it suggests that further research may reveal replication-timing changes as useful biomarkers for such diseases. The fact that it can now be measured with relative ease indicates that we will soon have a wealth of information about where and when large changes in chromosome folding occur during development and in different diseases.