Katana VentraIP

Superior vena cava

The superior vena cava (SVC) is the superior of the two venae cavae, the great venous trunks that return deoxygenated blood from the systemic circulation to the right atrium of the heart. It is a large-diameter (24 mm) short length vein that receives venous return from the upper half of the body, above the diaphragm. Venous return from the lower half, below the diaphragm, flows through the inferior vena cava. The SVC is located in the anterior right superior mediastinum.[1] It is the typical site of central venous access via a central venous catheter or a peripherally inserted central catheter. Mentions of "the cava" without further specification usually refer to the SVC.

This article uses anatomical terminology.

Superior vena cava

Clinical significance[edit]

Superior vena cava obstruction refers to a partial or complete obstruction of the superior vena cava, typically in the context of cancer such as a cancer of the lung, metastatic cancer, or lymphoma. Obstruction can lead to enlarged veins in the head and neck, and may also cause breathlessness, cough, chest pain, and difficulty swallowing. Pemberton's sign may be positive. Tumours causing obstruction may be treated with chemotherapy and/or radiotherapy to reduce their effects, and corticosteroids may also be given.[6]


In tricuspid valve regurgitation, these pulsations are very strong.


No valve divides the superior vena cava from the right atrium. As a result, the (right) atrial and (right) ventricular contractions are conducted up into the internal jugular vein and, through the sternocleidomastoid muscle, can be seen as the jugular venous pressure.

The thorax, viewed from the front, showing the superior vena cava between the heart and lungs.

The thorax, viewed from the front, showing the superior vena cava between the heart and lungs.

Heart seen from above, with the valve-less entry of the superior vena cava visible on the right.

Heart seen from above, with the valve-less entry of the superior vena cava visible on the right.

Superior vena cava in a cadaveric specimen.

Superior vena cava in a cadaveric specimen.

Cross-section of the thorax showing the formation of the superior vena cava.

Cross-section of the thorax showing the formation of the superior vena cava.

Persistent left superior vena cava

Superior vena cava syndrome

Inferior vena cava