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Acid–base reaction

In chemistry, an acid–base reaction is a chemical reaction that occurs between an acid and a base. It can be used to determine pH via titration. Several theoretical frameworks provide alternative conceptions of the reaction mechanisms and their application in solving related problems; these are called the acid–base theories, for example, Brønsted–Lowry acid–base theory.

"Acid–base" redirects here. For chemicals that can behave as acids or bases, see amphoterism.

Their importance becomes apparent in analyzing acid–base reactions for gaseous or liquid species, or when acid or base character may be somewhat less apparent. The first of these concepts was provided by the French chemist Antoine Lavoisier, around 1776.[1]


It is important to think of the acid–base reaction models as theories that complement each other.[2] For example, the current Lewis model has the broadest definition of what an acid and base are, with the Brønsted–Lowry theory being a subset of what acids and bases are, and the Arrhenius theory being the most restrictive.

Acid–base definitions[edit]

Historic development[edit]

The concept of an acid–base reaction was first proposed in 1754 by Guillaume-François Rouelle, who introduced the word "base" into chemistry to mean a substance which reacts with an acid to give it solid form (as a salt). Bases are mostly bitter in nature.[3]

Acid–base titration

Deprotonation

Donor number

Electron configuration

Gutmann–Beckett method

Lewis structure

Nucleophilic substitution

Neutralization (chemistry)

Protonation

reactions

Redox

Resonance (chemistry)

Clayden, Jonathan; Greeves, Nick; Warren, Stuart; Wothers, Peter (2015). Organic Chemistry (First ed.). Oxford University Press.

Finston, H.L.; Rychtman, A.C. (1983). A New View of Current Acid–Base Theories. New York: John Wiley & Sons.

Meyers, R. (2003). The Basics of Chemistry. Greenwood Press.

Miessler, G.L.; Tarr, D.A. (1991). Inorganic Chemistry.

– an on-line text

Acid–base Physiology

John W. Kimball's online biology book section of acid and bases.