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Lymphadenopathy

Lymphadenopathy or adenopathy is a disease of the lymph nodes, in which they are abnormal in size or consistency. Lymphadenopathy of an inflammatory type (the most common type) is lymphadenitis,[1] producing swollen or enlarged lymph nodes. In clinical practice, the distinction between lymphadenopathy and lymphadenitis is rarely made and the words are usually treated as synonymous. Inflammation of the lymphatic vessels is known as lymphangitis.[2] Infectious lymphadenitis affecting lymph nodes in the neck is often called scrofula.

Lymphadenopathy

Adenopathy, swollen lymph nodes, swollen glands

Fever; Hard, fixed, rapidly growing nodes, indicating a possible cancer or lymphoma; night sweats; runny nose; sore throat

Infections; autoimmune diseases; malignancies; histiocytoses; storage diseases; benign hyperplasia; drug reactions

Back pain; constipation; urinary frequency

Lymphadenopathy is a common and nonspecific sign. Common causes include infections (from minor causes such as the common cold and post-vaccination swelling to serious ones such as HIV/AIDS), autoimmune diseases, and cancer. Lymphadenopathy is frequently idiopathic and self-limiting.

[3]

Size, where lymphadenopathy in adults is often defined as a short axis of one or more lymph nodes is greater than 10mm.

[29]

Adenitis

Lymphovascular invasion

Archived 2012-06-02 at the Wayback Machine on humpath.com (Digital slides)

HPC:13820