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Sarah Gilbert

Dame Sarah Catherine Gilbert DBE FRS (born April 1962) is an English vaccinologist who is a Professor of Vaccinology at the University of Oxford and co-founder of Vaccitech.[2][3][4][5][6] She specialises in the development of vaccines against influenza and emerging viral pathogens.[7] She led the development and testing of the universal flu vaccine, which underwent clinical trials in 2011.

For the American actress, see Sara Gilbert.

In January 2020, she read a report on ProMED-mail about four people in China suffering from a strange kind of pneumonia of unknown origin in Wuhan.[8] Within two weeks, a vaccine had been designed at Oxford against the new pathogen, which later became known as COVID-19.[9] On 30 December 2020, the Oxford–AstraZeneca COVID-19 vaccine she co-developed with the Oxford Vaccine Group was approved for use in the UK.[10] As of January 2022, more than 2.5 billion doses of the vaccine have been released to more than 170 countries worldwide.[11]

Early life and education[edit]

Sarah Catherine Gilbert was born in Kettering, Northamptonshire. Her father was an office manager for a shoemakers and her mother was a primary school teacher.[12] Gilbert attended Kettering High School for Girls, where she realised that she wanted to work in medicine.[13][14] She earned nine O-Levels with six A grades.[13] She graduated with a Bachelor of Science degree in biological sciences from the University of East Anglia (UEA) in 1983.[15] While at UEA she began playing the saxophone, which she would practise in the woods around the UEA Broad so as not to disturb others in her halls.[13][16]


She moved to the University of Hull for her doctoral degree, where she investigated the genetics and biochemistry of the yeast Rhodosporidium toruloides, graduating with a PhD in 1986.[17][14]

Recognition[edit]

Gilbert was the subject of BBC Radio 4's The Life Scientific in September 2020.[42] She was also on the list of the BBC's 100 Women announced on 23 November 2020,[43] and became a senior associated research fellow at Christ Church, Oxford.[44] Gilbert was awarded the Rosalind Franklin medal for her services to science by Humanists UK at its annual Rosalind Franklin Lecture on 5 March 2021,[45] at which she delivered a lecture titled ‘Racing against the virus’. The lecture detailed the history of the science of vaccination and recounted the progress of the Oxford/AstraZeneca vaccine.[46]


In June 2021, Gilbert received a standing ovation at the 2021 Wimbledon Championships.[47] In 2021, as a role model (Barbie Shero), Sarah Gilbert had a Barbie doll made in her honour by the toy manufacturer Mattel.[48][49]

2021 – Rosalind Franklin Medal[46]

Humanists UK

2021 – of the Royal Society of Arts[50]

Albert Medal

2021 – (DBE) in the 2021 Birthday Honours for services to science and to public health in COVID-19 vaccine development[51]

Dame Commander of the Order of the British Empire

2021 – for Technical & Scientific Research[52]

Princess of Asturias Award

2021 – Gold Medal[53]

Royal Society of Medicine

2022 – Honorary doctorate of science from the [54]

University of East Anglia

2023 – in Medicine[55]

King Faisal Prize

2023 – (FRS)[56]

Fellow of the Royal Society

Personal life[edit]

Gilbert gave birth to triplets in 1998. Her partner gave up his career to be their primary parent.[14] As of 2020, all of the triplets are studying biochemistry at university.[12]

Schneider J; ; Blanchard TJ; et al. (1 April 1998). "Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara". Nature Medicine. 4 (4): 397–402. doi:10.1038/NM0498-397. ISSN 1078-8956. PMID 9546783. S2CID 11413461. Wikidata Q44138669.

Sarah Gilbert

McShane, H; Pathan, A A; Sander, C R; Keating, S M; Gilbert, S C; Huygen, K; Fletcher, H A; Hill, A V S (December 2004). . Nature Medicine. 10 (12): 1397. doi:10.1038/nm1204-1397a. ISSN 1078-8956.

"Erratum: Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans"

Samuel J McConkey; William H H Reece; Vasee S Moorthy; et al. (25 May 2003). . Nature Medicine. 9 (6): 729–735. doi:10.1038/NM881. ISSN 1078-8956. PMID 12766765. S2CID 6670274. Wikidata Q45723463.

"Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans"

; Plebanski M; Gupta S; et al. (1 February 1998). "Association of malaria parasite population structure, HLA, and immunological antagonism". Science. 279 (5354): 1173–1177. Bibcode:1998Sci...279.1173G. doi:10.1126/SCIENCE.279.5354.1173. ISSN 0036-8075. PMID 9469800. Wikidata Q47826329. Closed access icon

Sarah Gilbert

Gilbert, Sarah; Green, Catherine (2021). Vaxxers: the inside story of the Oxford AstraZeneca vaccine and the race against the virus. London: Hodder & Stoughton.  9781529369854.

ISBN

Gilbert has an h-index of 95 according to Google Scholar.[1] Her publications include:[57][58]

publications indexed by Google Scholar

Sarah Gilbert

on LinkedIn

Sarah Gilbert

In: La Repubblica, 17 July 2021 (Interview).

Oxford's Professor Sarah Gilbert: "The joys and frustrations of being a Covid vaccine maker".