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Great Barrington Declaration

The Great Barrington Declaration was an open letter published in October 2020 in response to the COVID-19 pandemic and lockdowns.[1][2] It claimed harmful COVID-19 lockdowns could be avoided via the fringe notion of "focused protection", by which those most at risk of dying from an infection could purportedly be kept safe while society otherwise took no steps to prevent infection.[3][4][5] The envisaged result was herd immunity within three months, as SARS-CoV-2 swept through the population.[1][2][4]

The Great Barrington Declaration

Signed by Sunetra Gupta of the University of Oxford, Jay Bhattacharya of Stanford University, and Martin Kulldorff of Harvard University, it was sponsored by the American Institute for Economic Research (AIER), a libertarian free-market think tank associated with climate change denial.[6][7][8] The declaration was drafted in Great Barrington, Massachusetts, signed there on 4 October 2020, and published on 5 October.[2][9] At the time, COVID-19 vaccines were considered to be months away from general availability.[4] The document presumed that the disease burden of mass infection could be tolerated, that any infection would confer long term sterilizing immunity, and it made no mention of physical distancing, masks, contact tracing,[10] or long COVID, which has left patients with debilitating symptoms months after the initial infection.[11][12]


The World Health Organization (WHO) and numerous academic and public-health bodies stated that the strategy would be dangerous and lacked a sound scientific basis.[13][14] They said that it would be challenging to shield all those who are medically vulnerable, leading to a large number of avoidable deaths among both older people and younger people with pre-existing health conditions,[15][16] and warned that the long-term effects of COVID-19 were still not fully understood.[14][17] Moreover, the WHO said that the herd immunity component of the proposed strategy is undermined by the unknown duration of post-infection immunity.[14][17] They said that the more likely outcome would be recurrent epidemics, as was the case with numerous infectious diseases before the advent of vaccination.[16] The American Public Health Association and 13 other public-health groups in the United States warned in a joint open letter that the "Great Barrington Declaration is not grounded in science and is dangerous".[13] The Great Barrington Declaration received support from some scientists, the Donald Trump administration, British Conservative politicians, and from The Wall Street Journal's editorial board.

Background and content

The idea to issue a declaration came from a conference run by the American Institute for Economic Research (AIER).[18] Gupta, one of the authors, said that given journals’ reluctance to publish on herd immunity and that the authors had been "repeatedly dismissed as fringe or pseudoscience" an open letter was chosen as the publication route out of necessity.[1]


The declaration says that lockdowns have adverse effects on physical and mental health, for example, because people postpone preventive healthcare.[19] They propose reducing these harms by ending mandatory restrictions on most activities for most people. Without these restrictions, more people will develop COVID-19. They believe that these infections will produce herd immunity (the idea that when enough people become immune, then the virus will stop circulating widely), which will eventually make it less likely that high-risk people will be exposed to the virus.[19]


The authors say that, instead of protecting everyone, the focus should instead be on "shielding" those most at risk, with few mandatory restrictions placed on the remainder of the population.[19] Stanford epidemiologist Yvonne Maldonado said that 40% of Americans have an elevated risk of dying from COVID-19, so this would require keeping the 40% of people with known risk factors away from the 60% of people without known risk factors.[20] In practice, such shielding is impossible to achieve.[3]


The declaration names specific economic changes that the signatories favour: resuming "life as normal", with schools and universities open for in-person teaching and extracurricular activities, re-opening offices, restaurants, and other places of work, and resuming mass gatherings for cultural and athletic activities. By October 2020, many of these things had already happened in some parts of the world,[9] but likewise were being restricted elsewhere; for instance the UK saw quarantines of students, travel advisories, restrictions on meeting other people, and partial closures of schools, pubs and restaurants.[21]


The declaration does not provide practical details about who should be protected or how they can be protected.[9] For instance, it does not mention testing any people outside of nursing homes, contact tracing, wearing masks, or social distancing.[9] It mentions multi-generational households but does not provide any information about how, for example, low-risk people can get infected without putting high-risk members of their household at risk of dying.[9]


The declaration does not provide any references to published data that support the declaration's strategy.[10]

The declaration was sponsored by the American Institute for Economic Research (AIER), a libertarian free market think tank based in Great Barrington, Massachusetts,[40][41] which has a history of promoting climate change denial,[42][43][44] and the benefits of sweatshops.[45][46] Byline Times journalist Nafeez Ahmed has described the AIER as an "institution embedded in a Koch-funded network that denies climate science while investing in polluting fossil fuel industries".[6]

Signatories

While the authors' website claims that over 14,000 scientists, 40,000 medical practitioners, and more than 800,000 members of the public signed the declaration,[47][48] this list—which anyone could sign online and which required merely clicking a checkbox to claim the status of "scientist"—contains some evidently-fake names, including: "Mr Banana Rama", "Harold Shipman", and "Prof Cominic Dummings".[49][50][51] More than 100 psychotherapists, numerous homeopaths, physiotherapists, massage therapists, and other non-relevant people were found to be signatories, including a performer of Khoomei—a Mongolian style of overtone singing—described as a "therapeutic sound practitioner".[50] An article in The Independent reported that the false signatures put claims about the breadth of support in doubt.[51] Bhattacharya responded by saying that the authors "did not have the resources to audit each signature," and that people had "abused our trust" by adding fake names.[51]

Counter memorandum

The John Snow Memorandum, the text of which was published simultaneously in The Lancet and dedicated site www.johnsnowmemo.com,[100][101][102] and built on a previous The Lancet correspondence piece,[103] is a response by 80 researchers denouncing the Great Barrington Declaration and its herd immunity approach.[20][104] Taking its name from John Snow, the epidemiologist who worked on the 1854 Broad Street cholera outbreak,[20][102] it states that the herd immunity idea is "a dangerous fallacy unsupported by the scientific evidence".[16] It acknowledges that COVID-19 restrictions have led to demoralization, making such an idea attractive, but states that "there is no evidence for lasting protective immunity to SARS-CoV-2", adding that "such a strategy would not lead to the end of COVID-19, but instead result in recurrent epidemics, as was the case with numerous infectious diseases before the advent of vaccination."[16]


The letter's authors were co-ordinated by Deepti Gurdasani, clinical epidemiologist at Queen Mary University of London,[105][106] and included researchers and clinicians such as Marc Lipsitch, William Hanage,[107][16] Nahid Bhadelia,[16] Isabella Eckerle,[108] Emma Hodcroft,[108] Florian Krammer,[109] Martin McKee,[110] Dominic Pimenta,[111] Viola Priesemann,[106] Devi Sridhar,[112] Gavin Yamey,[113] and Rochelle Walensky.[16][114]


Other signatories have included Reinhard Busse,[106] Christian Althaus,[108] Jacques Fellay,[108] Ilona Kickbusch,[108] and David Stuckler.[110]


In 2022, John Ioannidis, a scientist who has opposed prolonged COVID-19 lockdowns, authored a paper in BMJ Open arguing that signatories of the Great Barrington Declaration were shunned as a fringe minority by those in favor of the John Snow Memorandum. According to him, the latter used their large numbers of followers on Twitter and other social media and op-eds to shape a scientific "groupthink" against the former, who had less influence as measured by the Kardashian Index.[115][116] The BMJ published responses to his paper, including a comment by Gavin Yamey, David Gorski, and Gideon Meyerowitz-Katz which argued that Ioannidis's paper featured "factual errors, statistical shortcomings, failure to protect the named research subjects from harm, and potentially undeclared conflicts of interest that entirely undermine the analysis presented."[117]

a public health strategy pursued by some countries during the COVID-19 pandemic

Zero-COVID

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